Protocol Support

Every Protocol Your Lab Already Uses

ASTM E1394, HL7 v2.x, RS-232, and TCP/IP — all supported out of the box. No custom programming. No IT project. Just connect and go.

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ASTM E1394

Most Common

The standard serial protocol for clinical lab analyzers

ASTM E1394 is the communication standard used by nearly every clinical lab analyzer on the market. LISBridge fully implements the ENQ/ACK/EOT handshake and parses all H/P/O/R/L record types produced by 24+ supported instruments.

ENQ/ACK/EOT handshakeH/P/O/R/L record typesInstrument-specific variantsReal-time parsing
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HL7 v2.x

TCP Bidirectional

Hospital messaging standard — instrument-native HL7 parsing

HL7 v2.x is used by 95%+ of US hospitals for clinical data exchange. Several lab instruments (Abbott i800, Mindray BC-20s, Rayto CBC, Faca-280) send HL7 natively — LISBridge parses their ORU^R01 streams in real time over bidirectional TCP connections.

ORU^R01 inbound parsingMLLP frame detectionHL7 v2.3 – v2.5.1Bidirectional TCP socket
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RS-232 & TCP/IP

Dual Mode

Physical connection types — legacy and modern

RS-232 serial is still the most common physical interface on clinical analyzers. Modern instruments increasingly use TCP/IP over Ethernet. LISBridge supports both simultaneously — you can connect a legacy RS-232 analyzer and a modern TCP/IP analyzer in the same installation.

RS-232 auto-detectionUSB-to-serial adaptersTCP/IP client & serverSimultaneous connections
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How protocols work together in LISBridge

Your analyzer sends ASTM E1394 over RS-232 or TCP/IP. LISBridge receives it, parses it, structures the data, then forwards it to your HIS as an HL7 ORU message. The entire chain — in real time, without manual entry.

Analyzer
ASTM E1394
→
RS-232 / TCP/IP
Connection
→
LISBridge
Parser + Router
→
HIS / LIMS
HL7 ORU

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