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Device Connectivity

Old cable or network. Both work.

LISBridge connects to lab instruments over RS-232 serial or TCP/IP — at the same time, on the same installation. Legacy equipment works alongside your newest analyzers without replacing a single cable.

3
Connection types
35
Instruments
Auto
Instrument detection
< 5 min
To connect one instrument
Connection Types

Three ways to connect. One middleware.

No matter how old or new your analyzer is, there is a connection type that fits it.

🔌
RS-232 Serial
Legacy & modern

Most lab analyzers manufactured in the last 30 years have a serial port. LISBridge speaks that language natively — plug in the cable and the instrument starts sending data. No replacement, no adapters, no new hardware budget.

Works with any instrument that has a serial port
Standard baud rate, configurable per instrument
Auto-detects instrument type from the first message
Handles full send/acknowledge communication cycle
Supports simultaneous connections on multiple ports
Best for: haematology analysers, older chemistry instruments, any instrument with a DB-9 or DB-25 connector.
🌐
TCP/IP Network
Modern instruments

Modern analyzers connect over your hospital network. LISBridge listens on a configurable port and accepts connections from instruments directly — bidirectional, with no separate integration server required.

Configurable IP address and port per instrument
Bidirectional communication — send and receive
Works on your existing hospital network
IP Allowlist restricts connections to trusted sources
Supports HL7 MLLP framing out of the box
Best for: immunoassay analysers, newer chemistry systems, any instrument with an Ethernet port.
📁
FTP / FTPS / SFTP File Transport
File-based analysers

Some analysers never open a socket at all — they write result documents to a file server and read their orders back the same way. The bioMérieux VIDAS KUBE is the clearest example, exchanging aiMessage and lisMessage XML through the BCI Connect file server. Most middleware has no place to put an instrument like that. LISBridge treats file transport as a first-class connection tier: it watches the directory, reads results as they land, and writes orders back.

FTP, FTPS, and SFTP — encrypted transfer supported
Polls the configured directory for new result documents
Writes order documents back, so ordering stays bidirectional
XML result and order formats parsed natively (aiMessage / lisMessage)
Raw documents stored locally alongside the parsed result
Best for: bioMérieux VIDAS KUBE and any analyser that exchanges files with the LIS instead of streaming.
💡

Running a mixed lab? Both connection types work simultaneously on the same LISBridge installation. Your Sysmex on serial and your COBAS on TCP/IP connect through the same interface.

Setup

Connected in under 5 minutes

No IT project. No configuration file. Three steps and your instrument is live.

01
Plug in or configure

Connect the serial cable to your instrument's RS-232 port, or enter the IP address and port for a network-connected analyzer. That is all the setup required.

02
LISBridge identifies the instrument

The first message from the instrument tells LISBridge what it is. The correct parser and settings load automatically — no dropdown, no profile selection.

03
Results start flowing

From this point, every result the instrument produces is received, parsed, and forwarded to your HIS or LIMS automatically. Nothing else to do.

Always Connected

Connections that stay up

LISBridge is designed around the reality of clinical labs — instruments run 24 / 7 and downtime is not an option.

🔄
Auto-reconnects
If an instrument drops its connection, LISBridge detects the loss and re-establishes it without any action from your team. Retries use exponential backoff with jitter, so a briefly unreachable analyser recovers quickly and a genuinely offline one is not hammered.
🛡️
Crash-safe local storage
Results are written to a local SQLite database in write-ahead logging mode with connection pooling. A power cut or an unexpected restart does not cost you the results that had already arrived.
1️⃣
One instance, never two
A single-instance lock prevents a second copy of LISBridge from starting against the same instruments — including after an unclean shutdown, where a stale lock is detected and cleared rather than blocking startup.
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Restores on startup
Every active connection is stored. When LISBridge restarts, all instruments reconnect automatically — nothing to re-configure.
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Live connection status
Each instrument has its own status indicator in the dashboard — connected, receiving data, or offline at a glance.
⚡
Multiple instruments at once
RS-232 and TCP/IP connections run in parallel. A lab with 10 instruments connects all 10 through the same LISBridge installation.
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IP access control
For TCP/IP connections, you can lock access to a list of trusted IP addresses. Unauthorised devices on the network are blocked before they reach the parser.
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Auto-detects the instrument
LISBridge reads the first message from each instrument and identifies it automatically. The right parser loads without manual selection.
Security Posture

A gateway in front of a legacy analyser is a control, not a risk

Hospital IT asks a fair question before any middleware goes in: does putting another piece of software between the analyser and the LIS make our security position worse? For a device that cannot be upgraded, the recognised answer is the opposite — put a secure gateway in front of it, keep it segmented, and log what it does. That is a description of what LISBridge already is.

01
The analyser never has to change

A bench analyser bought in 2011 is not going to learn modern cryptography, and replacing it is rarely a real option. LISBridge speaks to it exactly as it is — RS-232, TCP/IP or file transport, in its own native dialect — so the device stays on its original firmware while the rest of the path around it is modernised.

02
Data stays local and encrypted

LISBridge is a native desktop application, not a cloud service. Results are written to encrypted local storage on a machine you already control. Patient data does not leave the site in order to be parsed, and an internet outage does not put results at risk.

03
Outbound only — no inbound ports

Orders are pulled from your HIS or HMS over an outbound connection and results are pushed back the same way. There is no inbound firewall rule to justify, no static IP to reserve, and no DMZ slot to negotiate for the HIS side of the integration.

04
An audit trail you can actually read

Every parsed result keeps the raw ASTM or HL7 frame that produced it. Liveness and panic logging record what the software was doing when it stopped. If someone asks what a given analyser sent at 02:14 last Tuesday, the answer is on disk.

05
Built in a memory-safe language

LISBridge is written in Rust, which rules out entire classes of memory-safety vulnerability at compile time — the same classes that dominate advisories for long-lived connected medical equipment.

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Doing a security review? Our full data-handling and retention position is written up on the data security page, and the parsing and raw-frame retention detail is on data parsing.

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